Bio Electric Surface

Biological Interactions with Surface Charge in Biomaterials

Tofail Syed (Editor)
ISBN: 978-1-84973-185-0
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Synopsis

When a biomaterial is placed inside the body, a biological response is triggered almost instantaneously. With devices that need to remain in the body for long periods, such interactions can cause encrustation, plaque formation and aseptic loosening on the surface. These problems contribute to the patient's trauma and increase the risk of death. Electrical properties, such as local electrostatic charge distribution, play a significant role in defining biological interactions, although this is often masked by other factors.

This book describes the fundamental principles of this phenomenon before providing a more detailed scientific background. It covers the development of the relevant technologies and their applications in therapeutic devices such as MRSA-resistant fabrics, cardiovascular and urological stents, orthopaedic implants, and grafts. Academic and graduate students interested in producing a selective biological response at the surface of a given biomaterial will find the detailed coverage of interactions at the nanometre scale useful. Practitioners will also benefit from guidance on how to pre-screen many inappropriate designs of biomedical devices long before any expensive, animal or potentially risky clinical trials.

Article title: In situ photoexcitation of silver doped titania nanopowders for activity against bacteria and yeasts

Journal title: Journal of Colloid And Interface Science

Abstract Photocatalytic and in situ microbial activity of the amorphous and annealed states of Ag-doped and un-doped titania, were examined. Studies on their structure, morphology, composition and the photo-absorption characteristics of these materials, were performed.